pentobarbital will reduce the extent or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will decrease the level or result of buprenorphine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Warning when discontinuing CYP3A4 inducers which have been coadmi… Read More